Member-only story
Why Making the Covid Vaccine was a Long Shot
An interview with David Heath, author of Longshot, reveals that government, businesses and many researchers discounted the science that made the COVID vaccine possible.
Longshot: The Inside Story of the Race for a COVID-19 Vaccine by award-winning investigative journalist David Heath exposes the political underside of how the race was won. Heath explains the complex chemistry involved in creating vaccines in understandable terms. He also describes the incredible challenges a handful of scientists faced in convincing other scientists and investors that making a COVID vaccine was possible.
This interview has been edited for brevity and clarity.
Vaccines have been used for a hundred years but explain how the COVID vaccine introduced a revolutionary new approach to making them.
The COVID-19 vaccines are among the greatest achievements of modern medicine. Never before have we developed a vaccine fast enough to tame a pandemic. Traditionally, vaccines were made of dead or weakened viruses. The mRNA approach uses the same method as our body’s DNA to produce a protein that mimics the virus, thus triggering our immune system. Scientists also built on HIV vaccine research to replicate the protein with unusual precision — a method Jonas Salk could have never imagined. That’s why the vaccines are so…